Cargando…

Pan-cancer clinical impact of latent drivers from double mutations

Here, we discover potential ‘latent driver’ mutations in cancer genomes. Latent drivers have low frequencies and minor observable translational potential. As such, to date they have escaped identification. Their discovery is important, since when paired in cis, latent driver mutations can drive canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Yavuz, Bengi Ruken, Tsai, Chung-Jung, Nussinov, Ruth, Tuncbag, Nurcan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941481/
https://www.ncbi.nlm.nih.gov/pubmed/36808143
http://dx.doi.org/10.1038/s42003-023-04519-5