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Identification of global inhibitors of cellular glycosylation

Small molecule inhibitors of glycosylation enzymes are valuable tools for dissecting glycan functions and potential drug candidates. Screening for inhibitors of glycosyltransferases are mainly performed by in vitro enzyme assays with difficulties moving candidates to cells and animals. Here, we circ...

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Detalles Bibliográficos
Autores principales: Sørensen, Daniel Madriz, Büll, Christian, Madsen, Thomas D., Lira-Navarrete, Erandi, Clausen, Thomas Mandel, Clark, Alex E., Garretson, Aaron F., Karlsson, Richard, Pijnenborg, Johan F. A., Yin, Xin, Miller, Rebecca L., Chanda, Sumit K., Boltje, Thomas J., Schjoldager, Katrine T., Vakhrushev, Sergey Y., Halim, Adnan, Esko, Jeffrey D., Carlin, Aaron F., Hurtado-Guerrero, Ramon, Weigert, Roberto, Clausen, Henrik, Narimatsu, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941569/
https://www.ncbi.nlm.nih.gov/pubmed/36804936
http://dx.doi.org/10.1038/s41467-023-36598-7