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Beneficial behavioral effects of chronic cerebral dopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington’s disease

Huntington’s disease (HD) is a progressive inherited neurological disease characterized by the degeneration of basal ganglia and the accumulation of mutant huntingtin (mHtt) aggregates in specific brain areas. Currently, there is no treatment for halting the progression of HD. Cerebral dopamine neur...

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Detalles Bibliográficos
Autores principales: Stepanova, P., Kumar, D., Cavonius, K., Korpikoski, J., Sirjala, J., Lindholm, D., Voutilainen, M. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941578/
https://www.ncbi.nlm.nih.gov/pubmed/36807563
http://dx.doi.org/10.1038/s41598-023-28798-4