Cargando…
Beneficial behavioral effects of chronic cerebral dopamine neurotrophic factor (CDNF) infusion in the N171-82Q transgenic model of Huntington’s disease
Huntington’s disease (HD) is a progressive inherited neurological disease characterized by the degeneration of basal ganglia and the accumulation of mutant huntingtin (mHtt) aggregates in specific brain areas. Currently, there is no treatment for halting the progression of HD. Cerebral dopamine neur...
Autores principales: | Stepanova, P., Kumar, D., Cavonius, K., Korpikoski, J., Sirjala, J., Lindholm, D., Voutilainen, M. H. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941578/ https://www.ncbi.nlm.nih.gov/pubmed/36807563 http://dx.doi.org/10.1038/s41598-023-28798-4 |
Ejemplares similares
-
Cerebral dopamine neurotrophic factor (CDNF) protects against quinolinic acid-induced toxicity in in vitro and in vivo models of Huntington’s disease
por: Stepanova, P., et al.
Publicado: (2020) -
CDNF and MANF in the brain dopamine system and their potential as treatment for Parkinson’s disease
por: Pakarinen, Emmi, et al.
Publicado: (2023) -
Intrastriatally Infused Exogenous CDNF Is Endocytosed and Retrogradely Transported to Substantia Nigra
por: Mätlik, Kert, et al.
Publicado: (2017) -
Association between cerebral dopamine neurotrophic factor (CDNF) 2 polymorphisms and schizophrenia susceptibility and symptoms in the Han Chinese population
por: Yang, Yongfeng, et al.
Publicado: (2018) -
Human-Specific Regulation of Neurotrophic Factors MANF and CDNF by microRNAs
por: Konovalova, Julia, et al.
Publicado: (2021)