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Fluorinated polyamidoamine dendrimer-mediated miR-23b delivery for the treatment of experimental rheumatoid arthritis in rats

In rheumatoid arthritis (RA), insufficient apoptosis of macrophages and excessive generation of pro-inflammatory cytokines are intimately connected, accelerating the development of disease. Here, a fluorinated polyamidoamine dendrimer (FP) is used to deliver miR-23b to reduce inflammation by trigger...

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Detalles Bibliográficos
Autores principales: Han, Haobo, Xing, Jiakai, Chen, Wenqi, Jia, Jiaxin, Li, Quanshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941585/
https://www.ncbi.nlm.nih.gov/pubmed/36805456
http://dx.doi.org/10.1038/s41467-023-36625-7