Digital expression profile of immune checkpoint genes in medulloblastomas identifies CD24 and CD276 as putative immunotherapy targets

INTRODUCTION: Medulloblastoma is the most common and lethal pediatric malignant brain tumor. It comprises four main molecular subgroups: WNT-activated, SHH-activated, Group 3, and Group 4. Medulloblastoma treatment is surgical resection, craniospinal radiation, and chemotherapy. However, many patien...

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Detalles Bibliográficos
Autores principales: Marques, Rui Ferreira, Moreno, Daniel Antunes, da Silva, Luciane, Leal, Leticia Ferro, de Paula, Flávia Escremim, Santana, Iara, Teixeira, Gustavo, Saggioro, Fabiano, Neder, Luciano, Junior, Carlos Almeida, Mançano, Bruna, Reis, Rui Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941636/
https://www.ncbi.nlm.nih.gov/pubmed/36825029
http://dx.doi.org/10.3389/fimmu.2023.1062856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941636/
https://www.ncbi.nlm.nih.gov/pubmed/36825029
http://dx.doi.org/10.3389/fimmu.2023.1062856

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