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A large-scale plasma proteome Mendelian randomization study identifies novel causal plasma proteins related to primary biliary cholangitis

BACKGROUND AND AIMS: Primary biliary cholangitis (PBC) is a progressive chronic autoimmune cholestatic liver disease characterized by the destruction of small intrahepatic bile ducts leading to biliary cirrhosis. Liver biopsy is required in the diagnosis of Antimitochondrial antibody-negative patien...

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Detalles Bibliográficos
Autores principales: Yang, Hongqun, Chen, Lanlan, Liu, Yahui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941641/
https://www.ncbi.nlm.nih.gov/pubmed/36825008
http://dx.doi.org/10.3389/fimmu.2023.1052616