Cargando…

A large-scale plasma proteome Mendelian randomization study identifies novel causal plasma proteins related to primary biliary cholangitis

BACKGROUND AND AIMS: Primary biliary cholangitis (PBC) is a progressive chronic autoimmune cholestatic liver disease characterized by the destruction of small intrahepatic bile ducts leading to biliary cirrhosis. Liver biopsy is required in the diagnosis of Antimitochondrial antibody-negative patien...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Hongqun, Chen, Lanlan, Liu, Yahui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941641/ https://www.ncbi.nlm.nih.gov/pubmed/36825008 http://dx.doi.org/10.3389/fimmu.2023.1052616

Ejemplares similares

Low vitamin D concentrations and BMI are causal factors for primary biliary cholangitis: A mendelian randomization study
por: Xu, Honglin, et al.
Publicado: (2022)

Plasma lipidomics of primary biliary cholangitis and its comparison with Sjögren’s syndrome
por: Li, Haolong, et al.
Publicado: (2023)

The Causal Effects of Primary Biliary Cholangitis on Thyroid Dysfunction: A Two-Sample Mendelian Randomization Study
por: Huang, Peng, et al.
Publicado: (2021)

Proteome-wide mendelian randomization identifies causal plasma proteins in venous thromboembolism development
por: Li, Haobo, et al.
Publicado: (2023)

Mendelian randomization rules out the causal relationship between serum lipids and cholecystitis
por: Yang, Hongqun, et al.
Publicado: (2021)

Causal associations between gut microbiota and primary biliary cholangitis: a bidirectional two-sample Mendelian randomization study
por: Zhang, Jiahao, et al.
Publicado: (2023)

Causal associations between inflammatory bowel disease and primary biliary cholangitis: a two-sample bidirectional Mendelian randomization study
por: Zhao, Jiaxi, et al.
Publicado: (2023)

Constitutive Activation of Natural Killer Cells in Primary Biliary Cholangitis
por: Hydes, Theresa J., et al.
Publicado: (2019)

The Salivary Microbiota of Patients With Primary Biliary Cholangitis Is Distinctive and Pathogenic
por: Lv, Longxian, et al.
Publicado: (2021)

Mendelian randomization analysis reveals causal effects of food intakes on inflammatory bowel disease risk
por: Chen, Bingxia, et al.
Publicado: (2022)

Concentration of Serum Matrix Metalloproteinase-3 in Patients With Primary Biliary Cholangitis
por: Bauer, Alicja, et al.
Publicado: (2022)

Effect of LncRNA XIST on Immune Cells of Primary Biliary Cholangitis
por: She, Chunhui, et al.
Publicado: (2022)

Gut microbial profile of treatment-naive patients with primary biliary cholangitis
por: Zhou, Yi-jun, et al.
Publicado: (2023)

Potential drug targets for asthma identified in the plasma and brain through Mendelian randomization analysis
por: Wang, Yuting, et al.
Publicado: (2023)

Dissecting the causal effect between gut microbiota, DHA, and urate metabolism: A large-scale bidirectional Mendelian randomization
por: Hou, Tianzhichao, et al.
Publicado: (2023)

Autoimmune biliary diseases: primary biliary cholangitis and primary sclerosing cholangitis
por: Sarcognato, Samantha, et al.
Publicado: (2021)

Changes of Serum IgG Glycosylation Patterns in Primary Biliary Cholangitis Patients
por: Zeng, Xiaoli, et al.
Publicado: (2021)

New insights on the role of human leukocyte antigen complex in primary biliary cholangitis
por: Mulinacci, Giacomo, et al.
Publicado: (2022)

Primary biliary cholangitis: molecular pathogenesis perspectives and therapeutic potential of natural products
por: Zhao, Yanling, et al.
Publicado: (2023)

The relation between plasma tyrosine concentration and fatigue in primary biliary cirrhosis and primary sclerosing cholangitis
por: ter Borg, Pieter CJ, et al.
Publicado: (2005)

Imbalance of the CD226/TIGIT Immune Checkpoint Is Involved in the Pathogenesis of Primary Biliary Cholangitis
por: Deng, Chuiwen, et al.
Publicado: (2020)

Mechanism-based target therapy in primary biliary cholangitis: opportunities before liver cirrhosis?
por: Yang, Yushu, et al.
Publicado: (2023)

Genetic link between primary sclerosing cholangitis and thyroid dysfunction: a bidirectional two-sample Mendelian randomization study
por: Zhang, Wenhui, et al.
Publicado: (2023)

Peroxisome Proliferator-Activated Receptors Regulate Hepatic Immunity and Assist in the Treatment of Primary Biliary Cholangitis
por: Wang, Chang, et al.
Publicado: (2022)

TR score: A noninvasive model to predict histological stages in patients with primary biliary cholangitis
por: Tu, Zhixin, et al.
Publicado: (2023)

Exploring pathogenesis of primary biliary cholangitis by proteomics: A pilot study
por: Deng, Chui-Wen, et al.
Publicado: (2017)

Osteoporosis in primary biliary cholangitis
por: Danford, Christopher J, et al.
Publicado: (2018)

Baricitinib and primary biliary cholangitis
por: Gordon, Stuart C., et al.
Publicado: (2021)

Genome-wide Mendelian randomization identifies putatively causal gut microbiota for multiple peptic ulcer diseases
por: Zhao, Jingwei, et al.
Publicado: (2023)

Antibodies to the Muscarinic Acetylcholine Receptor M3 in Primary Biliary Cholangitis Inhibit Receptor Function on Cholangiocytes
por: Mayer, Christian, et al.
Publicado: (2020)

Interleukin 23 Produced by Hepatic Monocyte-Derived Macrophages Is Essential for the Development of Murine Primary Biliary Cholangitis
por: Reuveni, Debby, et al.
Publicado: (2021)

Single-Cell Characterization of Hepatic CD8(+) T Cells in a Murine Model of Primary Biliary Cholangitis
por: Han, Yichen, et al.
Publicado: (2022)

Overlap Syndrome between Primary Biliary Cholangitis and Primary Sclerosing Cholangitis
por: Sundaram, Sridhar, et al.
Publicado: (2018)

Abnormal Expression of ERα in Cholangiocytes of Patients With Primary Biliary Cholangitis Mediated Intrahepatic Bile Duct Inflammation
por: Cao, Hui, et al.
Publicado: (2019)

Evaluation of the United Kingdom‐primary biliary cholangitis and global primary biliary cholangitis group prognostic models for primary biliary cholangitis patients treated with ursodeoxycholic acid in the U.S. population
por: Alomari, Mohammad, et al.
Publicado: (2019)

Causal association of circulating cytokines with sepsis: a Mendelian randomization study
por: Lin, Shan, et al.
Publicado: (2023)

Genetic predisposition of the gastrointestinal microbiome and primary biliary cholangitis: a bi-directional, two-sample Mendelian randomization analysis
por: Luo, Xin, et al.
Publicado: (2023)

Extrahepatic Manifestations of Primary Biliary Cholangitis
por: Chalifoux, Sara L, et al.
Publicado: (2017)

Obeticholic acid for primary biliary cholangitis
Publicado: (2020)

Current understanding of primary biliary cholangitis
por: Tanaka, Atsushi
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_tqahn5rpjguf47t80l5suuu4s2