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Bioequivalence study of ipratropium bromide inhalation aerosol using PBPK modelling

AIMS: Systemic pharmacokinetic (PK) studies can reflect the overall exposure of orally inhaled drug Products (OIDPs) in the blood after inhalation into the lung and can be used to evaluate the bioequivalence of test and reference products. The aim of this article is: (1) to study the PK characterist...

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Detalles Bibliográficos
Autores principales: Zhang, Jisheng, Wu, Keheng, Liu, Bo, Hou, Shuguang, Li, Xue, Ye, Xiang, Liu, Jack, He, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941642/
https://www.ncbi.nlm.nih.gov/pubmed/36824609
http://dx.doi.org/10.3389/fmed.2023.1056318