Aggrecan accumulates at sites of increased pulmonary arterial pressure in idiopathic pulmonary arterial hypertension

Expansion of extracellular matrix occurs in all stages of pulmonary angiopathy associated with pulmonary arterial hypertension (PAH). In systemic arteries, dysregulation and accumulation of the large chondroitin‐sulfate proteoglycan aggrecan is associated with swelling and disruption of vessel wall...

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Detalles Bibliográficos
Autores principales: van der Have, Oscar, Mead, Timothy J., Westöö, Christian, Peruzzi, Niccolò, Mutgan, Ayse C., Norvik, Christian, Bech, Martin, Struglics, André, Hoetzenecker, Konrad, Brunnström, Hans, Westergren‐Thorsson, Gunilla, Kwapiszewska, Grazyna, Apte, Suneel S., Tran‐Lundmark, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941846/
https://www.ncbi.nlm.nih.gov/pubmed/36824691
http://dx.doi.org/10.1002/pul2.12200

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9941846/
https://www.ncbi.nlm.nih.gov/pubmed/36824691
http://dx.doi.org/10.1002/pul2.12200

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