A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency

Eukaryotes have canonical pathways for responding to amino acid (AA) availability. Under AA-limiting conditions, the TOR complex is repressed, whereas the sensor kinase GCN2 is activated. While these pathways have been highly conserved throughout evolution, malaria parasites are a rare exception. De...

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Detalles Bibliográficos
Autores principales: Marreiros, Inês M., Marques, Sofia, Parreira, Ana, Mastrodomenico, Vincent, Mounce, Bryan C., Harris, Chantal T., Kafsack, Björn F., Billker, Oliver, Zuzarte-Luís, Vanessa, Mota, Maria M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942083/
https://www.ncbi.nlm.nih.gov/pubmed/36810637
http://dx.doi.org/10.1038/s42003-023-04566-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942083/
https://www.ncbi.nlm.nih.gov/pubmed/36810637
http://dx.doi.org/10.1038/s42003-023-04566-y

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