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Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome

[Image: see text] Here, we report a comprehensive profiling of sulfur(VI) fluorides (S(VI)-Fs) as reactive groups for chemical biology applications. S(VI)-Fs are reactive functionalities that modify lysine, tyrosine, histidine, and serine sidechains. A panel of S(VI)-Fs were studied with respect to...

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Detalles Bibliográficos
Autores principales: Gilbert, Katharine E., Vuorinen, Aini, Aatkar, Arron, Pogány, Peter, Pettinger, Jonathan, Grant, Emma K., Kirkpatrick, Joanna M., Rittinger, Katrin, House, David, Burley, Glenn A., Bush, Jacob T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942091/
https://www.ncbi.nlm.nih.gov/pubmed/36649130
http://dx.doi.org/10.1021/acschembio.2c00633