PTEN phosphatase inhibits metastasis by negatively regulating the Entpd5/IGF1R pathway through ATF6

PTEN encodes a tumor suppressor with lipid and protein phosphatase activities whose dysfunction has been implicated in melanomagenesis; less is known about how its phosphatases regulate melanoma metastasis. We demonstrate that PTEN expression negatively correlates with metastatic progression in huma...

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Detalles Bibliográficos
Autores principales: Yu, Yanlin, Dai, Meng, Huang, Liping, Chen, Weiping, Yu, Ellen, Mendoza, Arnulfo, Michael, Helen, Khanna, Chand, Bosenberg, Marcus, McMahon, Martin, Merlino, Glenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942123/
https://www.ncbi.nlm.nih.gov/pubmed/36824269
http://dx.doi.org/10.1016/j.isci.2023.106070

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942123/
https://www.ncbi.nlm.nih.gov/pubmed/36824269
http://dx.doi.org/10.1016/j.isci.2023.106070

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