Mechanistic Insights into the Ene-Reductase-Catalyzed Promiscuous Reduction of Oximes to Amines

[Image: see text] The biocatalytic reduction of the oxime moiety to the corresponding amine group has only recently been found to be a promiscuous activity of ene-reductases transforming α-oximo β-keto esters. However, the reaction pathway of this two-step reduction remained elusive. By studying the...

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Detalles Bibliográficos
Autores principales: Breukelaar, Willem B., Polidori, Nakia, Singh, Amit, Daniel, Bastian, Glueck, Silvia M., Gruber, Karl, Kroutil, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942197/
https://www.ncbi.nlm.nih.gov/pubmed/36846821
http://dx.doi.org/10.1021/acscatal.2c06137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942197/
https://www.ncbi.nlm.nih.gov/pubmed/36846821
http://dx.doi.org/10.1021/acscatal.2c06137

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