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Silencing Transcription from an Influenza Reverse Genetics Plasmid in E. coli Enhances Gene Stability

[Image: see text] Reverse genetics (RG) systems have been instrumental for determining the molecular aspects of viral replication, pathogenesis, and for the development of therapeutics. Here, we demonstrate that genes encoding the influenza surface antigens hemagglutinin and neuraminidase have varyi...

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Detalles Bibliográficos
Autores principales: Malik, Tahir, Klenow, Laura, Karyolaimos, Alexandros, Gier, Jan-Willem de, Daniels, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942234/
https://www.ncbi.nlm.nih.gov/pubmed/36716395
http://dx.doi.org/10.1021/acssynbio.2c00358