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A Ubiquitous Chromatin Opening Element and DNA Demethylation Facilitate Doxycycline-Controlled Expression during Differentiation and in Transgenic Mice

[Image: see text] Synthetic expression cassettes provide the ability to control transgene expression in experimental animal models through external triggers, enabling the study of gene function and the modulation of endogenous regulatory networks in vivo. The performance of synthetic expression cass...

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Detalles Bibliográficos
Autores principales: Gödecke, Natascha, Herrmann, Sabrina, Weichelt, Viola, Wirth, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942253/
https://www.ncbi.nlm.nih.gov/pubmed/36755406
http://dx.doi.org/10.1021/acssynbio.2c00450