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Melatonin attenuates high glucose‑induced endothelial cell pyroptosis by activating the Nrf2 pathway to inhibit NLRP3 inflammasome activation

Endothelial injury induced by hyperglycemia is the most critical initial step in the development of diabetic vasculopathy. The aim of this present study was to explore the prevention and treatment strategies and elucidate the specific mechanism of diabetes-induced vascular endothelial injury. Melato...

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Detalles Bibliográficos
Autores principales: Wang, Xuebin, Wang, Wei, Zhang, Rui, Ma, Baitao, Ni, Leng, Feng, Hai, Liu, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942260/
https://www.ncbi.nlm.nih.gov/pubmed/36799176
http://dx.doi.org/10.3892/mmr.2023.12958