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Fibroblast growth factor receptor type 4 as a potential therapeutic target in clear cell renal cell carcinoma

BACKGROUND: Several clear cell renal cell carcinoma (ccRCC) cases harbour fibroblast growth factor receptor 4 (FGFR4) gene copy number (CN) gains. In this study, we investigated the functional contribution of FGFR4 CN amplification in ccRCC. METHODS: The correlation between FGFR4 CN determined via r...

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Detalles Bibliográficos
Autores principales: Narisawa, Takafumi, Naito, Sei, Ito, Hiromi, Ichiyanagi, Osamu, Sakurai, Toshihiko, Kato, Tomoyuki, Tsuchiya, Norihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942348/
https://www.ncbi.nlm.nih.gov/pubmed/36803783
http://dx.doi.org/10.1186/s12885-023-10638-3