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Patterns of human and porcine gammaherpesvirus-encoded BILF1 receptor endocytosis

BACKGROUND: The viral G-protein-coupled receptor (vGPCR) BILF1 encoded by the Epstein–Barr virus (EBV) is an oncogene and immunoevasin and can downregulate MHC-I molecules at the surface of infected cells. MHC-I downregulation, which presumably occurs through co-internalization with EBV-BILF1, is pr...

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Detalles Bibliográficos
Autores principales: Mavri, Maša, Glišić, Sanja, Senćanski, Milan, Vrecl, Milka, Rosenkilde, Mette M., Spiess, Katja, Kubale, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942385/
https://www.ncbi.nlm.nih.gov/pubmed/36810008
http://dx.doi.org/10.1186/s11658-023-00427-y