Biophysical Correlates of Enhanced Immunogenicity of a Stabilized Variant of the Receptor Binding Domain of SARS-CoV-2

[Image: see text] The receptor binding domain (RBD) of SARS-CoV-2 is the primary target of neutralizing antibodies. We have previously reported the design and characterization of a mammalian cell expressed RBD derivative, mRBD1-3.2, that has higher thermal stability and greatly enhanced immunogenici...

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Detalles Bibliográficos
Autores principales: Kanjo, Kawkab, Chattopadhyay, Gopinath, Malladi, Sameer Kumar, Singh, Randhir, Jayatheertha, Sowrabha, Varadarajan, Raghavan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942533/
https://www.ncbi.nlm.nih.gov/pubmed/36790910
http://dx.doi.org/10.1021/acs.jpcb.2c07262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942533/
https://www.ncbi.nlm.nih.gov/pubmed/36790910
http://dx.doi.org/10.1021/acs.jpcb.2c07262

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