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Study on molecular mechanisms of CD4 dependency and independency of HIV-1 gp120

Different HIV-1 strains have different antibody neutralization phenotypes (or CD4-dependencies). However, the molecular mechanisms underlying these differences remain to be elucidated. In this study, we constructed gp120 structural models from the CD4-dependent, neutralization-resistant JR-FL strain...

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Detalles Bibliográficos
Autores principales: Liu, Meng-Ting, Shen, Jian-Xin, Li, Xin-Wei, Yang, Li, Li, Yi, Sang, Peng, Yang, Li-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942563/
https://www.ncbi.nlm.nih.gov/pubmed/36825290
http://dx.doi.org/10.1039/d3ra00433c