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Apurinic/apyrimidinic endonuclease 1 is associated with poor prognosis after curative resection followed by adjuvant chemotherapy in patients with stage III colon cancer

PURPOSE: Apurinic/apyrimidinic endonuclease 1 (APE1) is a key enzyme involved in the base excision repair pathway. It also has redox activity and maintains various transcription factors in an active reduced state. APE1 may be associated with chemoresistance. In the present study, we first investigat...

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Detalles Bibliográficos
Autores principales: Song, Ji Hyeong, Lee, Myung Sun, Cha, Eun Young, Lee, Kyung Ha, Kim, Ji Yeon, Kim, Jin Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Surgical Oncology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942767/
https://www.ncbi.nlm.nih.gov/pubmed/36945334
http://dx.doi.org/10.14216/kjco.22001