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Measures of epitope binding degeneracy from T cell receptor repertoires
Adaptive immunity is driven by specific binding of hypervariable receptors to diverse molecular targets. The sequence diversity of receptors and targets are both individually known but because multiple receptors can recognize the same target, a measure of the effective “functional” diversity of the...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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National Academy of Sciences
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942805/ https://www.ncbi.nlm.nih.gov/pubmed/36649423 http://dx.doi.org/10.1073/pnas.2213264120 |