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Origins of genome-editing excisases as illuminated by the somatic genome of the ciliate Blepharisma

Massive DNA excision occurs regularly in ciliates, ubiquitous microbial eukaryotes with somatic and germline nuclei in the same cell. Tens of thousands of internally eliminated sequences (IESs) scattered throughout the ciliate germline genome are deleted during the development of the streamlined som...

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Detalles Bibliográficos
Autores principales: Singh, Minakshi, Seah, Brandon K.B., Emmerich, Christiane, Singh, Aditi, Woehle, Christian, Huettel, Bruno, Byerly, Adam, Stover, Naomi A., Sugiura, Mayumi, Harumoto, Terue, Swart, Estienne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942806/
https://www.ncbi.nlm.nih.gov/pubmed/36669098
http://dx.doi.org/10.1073/pnas.2213887120