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Origins of genome-editing excisases as illuminated by the somatic genome of the ciliate Blepharisma
Massive DNA excision occurs regularly in ciliates, ubiquitous microbial eukaryotes with somatic and germline nuclei in the same cell. Tens of thousands of internally eliminated sequences (IESs) scattered throughout the ciliate germline genome are deleted during the development of the streamlined som...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942806/ https://www.ncbi.nlm.nih.gov/pubmed/36669098 http://dx.doi.org/10.1073/pnas.2213887120 |