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Mosaic RBD nanoparticles induce intergenus cross-reactive antibodies and protect against SARS-CoV-2 challenge

Recurrent spillovers of α- and β-coronaviruses (CoV) such as severe acute respiratory syndrome (SARS)-CoV, Middle East respiratory syndrome-CoV, SARS-CoV-2, and possibly human CoV have caused serious morbidity and mortality worldwide. In this study, six receptor-binding domains (RBDs) derived from α...

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Detalles Bibliográficos
Autores principales: Lee, Dan Bi, Kim, Hyojin, Jeong, Ju Hwan, Jang, Ui Soon, Jang, Yuyeon, Roh, Seokbeom, Jeon, Hyunbum, Kim, Eun Jeong, Han, Su Yeon, Maeng, Jin Young, Magez, Stefan, Radwanska, Magdalena, Mun, Ji Young, Jun, Hyun Sik, Lee, Gyudo, Song, Min-Suk, Lee, Hye-Ra, Chung, Mi Sook, Baek, Yun Hee, Kim, Kyung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942827/
https://www.ncbi.nlm.nih.gov/pubmed/36669119
http://dx.doi.org/10.1073/pnas.2208425120