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Genome-wide analysis of heat stress-stimulated transposon mobility in the human fungal pathogen Cryptococcus deneoformans

We recently reported transposon mutagenesis as a significant driver of spontaneous mutations in the human fungal pathogen Cryptococcus deneoformans during murine infection. Mutations caused by transposable element (TE) insertion into reporter genes were dramatically elevated at high temperatures (37...

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Detalles Bibliográficos
Autores principales: Gusa, Asiya, Yadav, Vikas, Roth, Cullen, Williams, Jonathan D., Shouse, Eva Mei, Magwene, Paul, Heitman, Joseph, Jinks-Robertson, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942834/
https://www.ncbi.nlm.nih.gov/pubmed/36669112
http://dx.doi.org/10.1073/pnas.2209831120