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Structural remodeling of AAA+ ATPase p97 by adaptor protein ASPL facilitates posttranslational methylation by METTL21D

p97 is an essential AAA+ ATPase that extracts and unfolds substrate proteins from membranes and protein complexes. Through its mode of action, p97 contributes to various cellular processes, such as membrane fusion, ER-associated protein degradation, DNA repair, and many others. Diverse p97 functions...

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Detalles Bibliográficos
Autores principales: Petrović, Saša, Roske, Yvette, Rami, Biria, Phan, Mai Hoang Quynh, Panáková, Daniela, Heinemann, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942839/
https://www.ncbi.nlm.nih.gov/pubmed/36656859
http://dx.doi.org/10.1073/pnas.2208941120