Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids

Nonvesicular extracellular RNAs (nv-exRNAs) constitute the majority of the extracellular RNAome, but little is known about their stability, function, and potential use as disease biomarkers. Herein, we measured the stability of several naked RNAs when incubated in human serum, urine, and cerebrospin...

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Detalles Bibliográficos
Autores principales: Costa, Bruno, Li Calzi, Marco, Castellano, Mauricio, Blanco, Valentina, Cuevasanta, Ernesto, Litvan, Irene, Ivanov, Pavel, Witwer, Kenneth, Cayota, Alfonso, Tosar, Juan Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942843/
https://www.ncbi.nlm.nih.gov/pubmed/36652478
http://dx.doi.org/10.1073/pnas.2216330120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942843/
https://www.ncbi.nlm.nih.gov/pubmed/36652478
http://dx.doi.org/10.1073/pnas.2216330120

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