Repurposing HDAC inhibitors to enhance ribonuclease 4 and 7 expression and reduce urinary tract infection

With the emergence of antibiotic-resistant bacteria, innovative approaches are needed for the treatment of urinary tract infections. Boosting antimicrobial peptide expression may provide an alternative to antibiotics. Here, we developed reporter cell lines and performed a high-throughput screen of c...

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Detalles Bibliográficos
Autores principales: Schwartz, Laura, Bochter, M. Skye, Simoni, Aaron, Bender, Kristin, de Dios Ruiz Rosado, Juan, Cotzomi-Ortega, Israel, Sanchez-Zamora, Yuriko I., Becknell, Brian, Linn, Sarah, Li, Birong, Santoro, Nicholas, Eichler, Tad, Spencer, John David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942862/
https://www.ncbi.nlm.nih.gov/pubmed/36652479
http://dx.doi.org/10.1073/pnas.2213363120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942862/
https://www.ncbi.nlm.nih.gov/pubmed/36652479
http://dx.doi.org/10.1073/pnas.2213363120

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