Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals

Resting skeletal muscle generates heat for endothermy in mammals but not amphibians, while both use the same Ca(2+)-handling proteins and membrane structures to conduct excitation–contraction coupling apart from having different ryanodine receptor (RyR) isoforms for Ca(2+) release. The sarcoplasmic...

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Detalles Bibliográficos
Autores principales: Singh, Daniel P., Pearce, Luke, Choi, Rocky H., Meizoso-Huesca, Aldo, Wette, Stefan G., Scott, John W., Lamboley, Cedric R., Murphy, Robyn M., Launikonis, Bradley S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942912/
https://www.ncbi.nlm.nih.gov/pubmed/36649401
http://dx.doi.org/10.1073/pnas.2117503120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942912/
https://www.ncbi.nlm.nih.gov/pubmed/36649401
http://dx.doi.org/10.1073/pnas.2117503120

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