Cargando…
Evolutionary isolation of ryanodine receptor isoform 1 for muscle-based thermogenesis in mammals
Resting skeletal muscle generates heat for endothermy in mammals but not amphibians, while both use the same Ca(2+)-handling proteins and membrane structures to conduct excitation–contraction coupling apart from having different ryanodine receptor (RyR) isoforms for Ca(2+) release. The sarcoplasmic...
Autores principales: | Singh, Daniel P., Pearce, Luke, Choi, Rocky H., Meizoso-Huesca, Aldo, Wette, Stefan G., Scott, John W., Lamboley, Cedric R., Murphy, Robyn M., Launikonis, Bradley S. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942912/ https://www.ncbi.nlm.nih.gov/pubmed/36649401 http://dx.doi.org/10.1073/pnas.2117503120 |
Ejemplares similares
-
Ca(2+) leak through ryanodine receptor 1 regulates thermogenesis in resting skeletal muscle
por: Meizoso-Huesca, Aldo, et al.
Publicado: (2022) -
Ryanodine receptor leak triggers fiber Ca(2+) redistribution to preserve force and elevate basal metabolism in skeletal muscle
por: Lamboley, Cedric R., et al.
Publicado: (2021) -
The Orai1 inhibitor BTP2 has multiple effects on Ca(2+) handling in skeletal muscle
por: Meizoso-Huesca, Aldo, et al.
Publicado: (2020) -
Muscle nonshivering thermogenesis in a feral mammal
por: Nowack, Julia, et al.
Publicado: (2019) -
A bivalent remipede toxin promotes calcium release via ryanodine receptor activation
por: Maxwell, Michael J., et al.
Publicado: (2023)