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Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor

Sarcopenia is distinct from normal muscle atrophy in that it is closely related to a shift in the muscle fiber type. Deficiency of the anabolic action of androgen on skeletal muscles is associated with sarcopenia; however, the function of the androgen receptor (AR) pathway in sarcopenia remains poor...

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Detalles Bibliográficos
Autores principales: Hosoi, Tatsuya, Yakabe, Mitsutaka, Sasakawa, Hiroko, Sasako, Takayoshi, Ueki, Kohjiro, Kato, Shigeaki, Tokuoka, Suzumi M., Oda, Yoshiya, Abe, Masahiro, Matsumoto, Toshio, Akishita, Masahiro, Ogawa, Sumito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942915/
https://www.ncbi.nlm.nih.gov/pubmed/36669097
http://dx.doi.org/10.1073/pnas.2218032120