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Sarcopenia phenotype and impaired muscle function in male mice with fast-twitch muscle-specific knockout of the androgen receptor
Sarcopenia is distinct from normal muscle atrophy in that it is closely related to a shift in the muscle fiber type. Deficiency of the anabolic action of androgen on skeletal muscles is associated with sarcopenia; however, the function of the androgen receptor (AR) pathway in sarcopenia remains poor...
Autores principales: | Hosoi, Tatsuya, Yakabe, Mitsutaka, Sasakawa, Hiroko, Sasako, Takayoshi, Ueki, Kohjiro, Kato, Shigeaki, Tokuoka, Suzumi M., Oda, Yoshiya, Abe, Masahiro, Matsumoto, Toshio, Akishita, Masahiro, Ogawa, Sumito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942915/ https://www.ncbi.nlm.nih.gov/pubmed/36669097 http://dx.doi.org/10.1073/pnas.2218032120 |
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