Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable

X-chromosome inactivation (XCI) silences one X in female cells to balance sex-differences in X-dosage. A subset of X-linked genes escape XCI, but the extent to which this phenomenon occurs and how it varies across tissues and in a population is as yet unclear. To characterize incidence and variabili...

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Detalles Bibliográficos
Autores principales: Zito, Antonino, Roberts, Amy L., Visconti, Alessia, Rossi, Niccolo’, Andres-Ejarque, Rosa, Nardone, Stefano, El-Sayed Moustafa, Julia S., Falchi, Mario, Small, Kerrin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942974/
https://www.ncbi.nlm.nih.gov/pubmed/36802379
http://dx.doi.org/10.1371/journal.pgen.1010556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942974/
https://www.ncbi.nlm.nih.gov/pubmed/36802379
http://dx.doi.org/10.1371/journal.pgen.1010556

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