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Escape from X-inactivation in twins exhibits intra- and inter-individual variability across tissues and is heritable
X-chromosome inactivation (XCI) silences one X in female cells to balance sex-differences in X-dosage. A subset of X-linked genes escape XCI, but the extent to which this phenomenon occurs and how it varies across tissues and in a population is as yet unclear. To characterize incidence and variabili...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942974/ https://www.ncbi.nlm.nih.gov/pubmed/36802379 http://dx.doi.org/10.1371/journal.pgen.1010556 |