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Conditional ablation of heparan sulfate expression in stromal fibroblasts promotes tumor growth in vivo
Heparan sulfate (HS) is a glycocalyx component present in the extracellular matrix and cell-surface HS proteoglycans (HSPGs). Although HSPGs are known to play functional roles in multiple aspects of tumor development and progression, the effect of HS expression in the tumor stroma on tumor growth in...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942975/ https://www.ncbi.nlm.nih.gov/pubmed/36809261 http://dx.doi.org/10.1371/journal.pone.0281820 |