Conditional ablation of heparan sulfate expression in stromal fibroblasts promotes tumor growth in vivo

Heparan sulfate (HS) is a glycocalyx component present in the extracellular matrix and cell-surface HS proteoglycans (HSPGs). Although HSPGs are known to play functional roles in multiple aspects of tumor development and progression, the effect of HS expression in the tumor stroma on tumor growth in...

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Detalles Bibliográficos
Autores principales: Niwa, Ayumi, Taniguchi, Toshiaki, Tomita, Hiroyuki, Okada, Hideshi, Kinoshita, Takamasa, Mizutani, Chika, Matsuo, Mikiko, Imaizumi, Yuko, Kuroda, Takahito, Ichihashi, Koki, Sugiyama, Takaaki, Kanayama, Tomohiro, Yamaguchi, Yu, Sugie, Shigeyuki, Matsuhashi, Nobuhisa, Hara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9942975/
https://www.ncbi.nlm.nih.gov/pubmed/36809261
http://dx.doi.org/10.1371/journal.pone.0281820

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