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Targeted anatomical and functional identification of antinociceptive and pronociceptive serotonergic neurons that project to the spinal dorsal horn

Spinally projecting serotonergic neurons play a key role in controlling pain sensitivity and can either increase or decrease nociception depending on physiological context. It is currently unknown how serotonergic neurons mediate these opposing effects. Utilizing virus-based strategies and Tph2-Cre...

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Detalles Bibliográficos
Autores principales: Ganley, Robert Philip, de Sousa, Marilia Magalhaes, Werder, Kira, Öztürk, Tugce, Mendes, Raquel, Ranucci, Matteo, Wildner, Hendrik, Zeilhofer, Hanns Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943064/
https://www.ncbi.nlm.nih.gov/pubmed/36752606
http://dx.doi.org/10.7554/eLife.78689