Nuclear export inhibition jumbles epithelial–mesenchymal states and gives rise to migratory disorder in healthy epithelia

Dynamic nucleocytoplasmic transport of E-M factors regulates cellular E-M states; yet, it remains unknown how simultaneously trapping these factors affects epithelia at the macroscale. To explore this question, we performed nuclear export inhibition (NEI) via leptomycin B and Selinexor treatment, wh...

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Detalles Bibliográficos
Autores principales: Krull, Carly M, Li, Haiyi, Pathak, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Physics of Living Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943065/
https://www.ncbi.nlm.nih.gov/pubmed/36805020
http://dx.doi.org/10.7554/eLife.81048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943065/
https://www.ncbi.nlm.nih.gov/pubmed/36805020
http://dx.doi.org/10.7554/eLife.81048

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