IDO1 Activity Predicts Lung Toxicity in Patients with Unresectable Stage III NSCLC and Chemoradiotherapy

OBJECTIVES: Indoleamine 2,3-dioxygenase 1 (IDO1) acts as the key rate-limiting enzyme that converts tryptophan (Trp) to kynurenine (Kyn). Its activity was primarily induced by interferon-γ (IFN-γ), which was reported to play a role in the development of acute radiation-induced pneumonitis. In this s...

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Detalles Bibliográficos
Autores principales: Wu, Linfang, Gao, Yibo, Wang, Daquan, Chen, Yanhua, Qian, Mingmin, Xu, Xin, Zhang, Tao, Bi, Nan, Wang, Luhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943611/
https://www.ncbi.nlm.nih.gov/pubmed/36824664
http://dx.doi.org/10.1155/2023/3591758

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943611/
https://www.ncbi.nlm.nih.gov/pubmed/36824664
http://dx.doi.org/10.1155/2023/3591758

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