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CS27109, A Selective Thyroid Hormone Receptor-β Agonist Alleviates Metabolic-Associated Fatty Liver Disease in Murine Models

BACKGROUND/AIM: Thyroid hormone receptor-β (THR-β) agonists play crucial roles in dyslipidemia and metabolic associated fatty liver disease (MAFLD). We developed a novel oral and liver-targeted THR-β agonist, CS27109, and evaluated its efficacy in the treatment of metabolic disorders. MATERIALS AND...

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Detalles Bibliográficos
Autores principales: Huang, Shengjian, Deng, Zhou, Wang, Wei, Liao, Guoqiang, Zhao, Yiru, Zhong, Hua, Zhang, Qian, Liu, Jing, Mao, Xuhua, Chen, Beizhong, Pan, Desi, Zhou, You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943626/
https://www.ncbi.nlm.nih.gov/pubmed/36825196
http://dx.doi.org/10.1155/2023/4950597