A scanning-to-incision switch in TFIIH-XPG induced by DNA damage licenses nucleotide excision repair

Nucleotide excision repair (NER) is critical for removing bulky DNA base lesions and avoiding diseases. NER couples lesion recognition by XPC to strand separation by XPB and XPD ATPases, followed by lesion excision by XPF and XPG nucleases. Here, we describe key regulatory mechanisms and roles of XP...

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Detalles Bibliográficos
Autores principales: Bralić, Amer, Tehseen, Muhammad, Sobhy, Mohamed A, Tsai, Chi-Lin, Alhudhali, Lubna, Yi, Gang, Yu, Jina, Yan, Chunli, Ivanov, Ivaylo, Tsutakawa, Susan E, Tainer, John A, Hamdan, Samir M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
NAR Breakthrough Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943652/
https://www.ncbi.nlm.nih.gov/pubmed/36477609
http://dx.doi.org/10.1093/nar/gkac1095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943652/
https://www.ncbi.nlm.nih.gov/pubmed/36477609
http://dx.doi.org/10.1093/nar/gkac1095

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