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Hierarchical DNA branch assembly-encoded fluorescent nanoladders for single-cell transcripts imaging

Spatial visualization of single-cell transcripts is limited by signal specificity and multiplexing. Here, we report hierarchical DNA branch assembly-encoded fluorescent nanoladders, which achieve denoised and highly multiplexed signal amplification for single-molecule transcript imaging. This method...

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Detalles Bibliográficos
Autores principales: Cao, Xiaowen, Chen, Feng, Xue, Jing, Zhao, Yue, Bai, Min, Zhao, Yongxi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943671/
https://www.ncbi.nlm.nih.gov/pubmed/36478047
http://dx.doi.org/10.1093/nar/gkac1138