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Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres

Protein phosphatase magnesium-dependent 1 delta (PPM1D) terminates the cell cycle checkpoint by dephosphorylating the tumour suppressor protein p53. By targeting additional substrates at chromatin, PPM1D contributes to the control of DNA damage response and DNA repair. Using proximity biotinylation...

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Detalles Bibliográficos
Autores principales: Storchova, Radka, Palek, Matous, Palkova, Natalie, Veverka, Pavel, Brom, Tomas, Hofr, Ctirad, Macurek, Libor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943673/
https://www.ncbi.nlm.nih.gov/pubmed/36651296
http://dx.doi.org/10.1093/nar/gkac1269