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Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres
Protein phosphatase magnesium-dependent 1 delta (PPM1D) terminates the cell cycle checkpoint by dephosphorylating the tumour suppressor protein p53. By targeting additional substrates at chromatin, PPM1D contributes to the control of DNA damage response and DNA repair. Using proximity biotinylation...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943673/ https://www.ncbi.nlm.nih.gov/pubmed/36651296 http://dx.doi.org/10.1093/nar/gkac1269 |