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Graded impact of obstacle size on scanning by RNase E

In countless bacterial species, the lifetimes of most mRNAs are controlled by the regulatory endonuclease RNase E, which preferentially degrades RNAs bearing a 5′ monophosphate and locates cleavage sites within them by scanning linearly from the 5′ terminus along single-stranded regions. Consequentl...

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Detalles Bibliográficos
Autores principales: Richards, Jamie, Belasco, Joel G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943677/
https://www.ncbi.nlm.nih.gov/pubmed/36620905
http://dx.doi.org/10.1093/nar/gkac1242