Snapshots of the first-step self-splicing of Tetrahymena ribozyme revealed by cryo-EM

Tetrahymena ribozyme is a group I intron, whose self-splicing is the result of two sequential ester-transfer reactions. To understand how it facilitates catalysis in the first self-splicing reaction, we used cryogenic electron microscopy (cryo-EM) to resolve the structures of L-16 Tetrahymena ribozy...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaojing, Li, Shanshan, Pintilie, Grigore, Palo, Michael Z, Zhang, Kaiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943679/
https://www.ncbi.nlm.nih.gov/pubmed/36660826
http://dx.doi.org/10.1093/nar/gkac1268

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943679/
https://www.ncbi.nlm.nih.gov/pubmed/36660826
http://dx.doi.org/10.1093/nar/gkac1268

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