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Unsupervised discovery of ancestry-informative markers and genetic admixture proportions in biobank-scale datasets
Admixture estimation plays a crucial role in ancestry inference and genome-wide association studies (GWASs). Computer programs such as ADMIXTURE and STRUCTURE are commonly employed to estimate the admixture proportions of sample individuals. However, these programs can be overwhelmed by the computat...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943729/ https://www.ncbi.nlm.nih.gov/pubmed/36610401 http://dx.doi.org/10.1016/j.ajhg.2022.12.008 |