Unsupervised discovery of ancestry-informative markers and genetic admixture proportions in biobank-scale datasets

Admixture estimation plays a crucial role in ancestry inference and genome-wide association studies (GWASs). Computer programs such as ADMIXTURE and STRUCTURE are commonly employed to estimate the admixture proportions of sample individuals. However, these programs can be overwhelmed by the computat...

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Detalles Bibliográficos
Autores principales: Ko, Seyoon, Chu, Benjamin B., Peterson, Daniel, Okenwa, Chidera, Papp, Jeanette C., Alexander, David H., Sobel, Eric M., Zhou, Hua, Lange, Kenneth L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943729/
https://www.ncbi.nlm.nih.gov/pubmed/36610401
http://dx.doi.org/10.1016/j.ajhg.2022.12.008

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