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Agonist-controlled competition of RAR and VDR nuclear receptors for heterodimerization with RXR is manifested in their DNA binding

We found previously that nuclear receptors (NRs) compete for heterodimerization with their common partner, retinoid X receptor (RXR), in a ligand-dependent manner. To investigate potential competition in their DNA binding, we monitored the mobility of retinoic acid receptor (RAR) and vitamin D recep...

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Detalles Bibliográficos
Autores principales: Rehó, Bálint, Fadel, Lina, Brazda, Peter, Benziane, Anass, Hegedüs, Éva, Sen, Pialy, Gadella, Theodorus W.J., Tóth, Katalin, Nagy, László, Vámosi, György
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9943875/
https://www.ncbi.nlm.nih.gov/pubmed/36639026
http://dx.doi.org/10.1016/j.jbc.2023.102896